Research in:
biotechnology, biologics
and tissue engineering

About us
Top Health, S.A.P.I. de C.V. (Top Health) was founded in 2013 as a result of the normal course of Corporate Group IMT by Eng. José Adán Ortega Blanco, a visionary and entrepreneurial man. The desire to enter the field of health through tissue engineering and create alternatives in the area of regenerative medicine, through the use of cell and tissue therapy, led him to form a multidisciplinary group of high-level professionals (doctors, chemists, engineers and administrative staff).
Top Health develops medical devices of human origin and tissue engineering for its application in therapies such as: bone defects, skin wounds and ophthalmological injuries, resulting in wellness and improvement in the quality of life of people.

Cellular therapy
- Immuno-modulatory capacity (regulation of the immune system)
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Stimulation of reparative processes in the body at the molecular level.
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Potential to migrate to other cell lineages
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Promote tissue healing through local secretion of cytokines and growth factors.
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Contribute to the regeneration of bone and cartilage tissues.
- Rheumatology
- Orthopedics and Traumatology
- Aesthetic medicine
Mesenchymal Stem Cells isolation (MSC) and cultivation is performed using GMP (Good Manufacturing Practices) products and reagents completely free of animal components.
Advanced center of musculoskeletal tissue, amnions and skin
ALLOGRAFT BIO IMPLANTS
LYOPHILIZED BIOLOGICALS

CANCELLOUS BONE POWDER

CORTICO-CANCELLOUS BONE POWDER

CANCELLOUS BONE GRANULE

CORTICO-CANCELLOUS BONE GRANULE

CANCELLOUS BONE CHIP

CORTICO-CANCELLOUS BONE CHIP

CANCELLOUS BONE BLOCK

DEMINERALIZED BONE MATRIX

CORTICAL BONE STRIP

BICORTICAL BONE STRIP

TRICORTICAL BONE STRIP

BONE DIAPHYSIS OF FIBULA

BONE DIAPHYSIS OF ULNA

BONE DIAPHYSIS OF HUMERUS

BONE DIAPHYSIS OF RADIUS

BONE DIAPHYSIS OF FEMUR

BONE DIAPHYSIS OF TIBIA
FROZEN BIOLOGICALS

ACHILLES TENDON

ACHILLES HEMITENDON

ANTERIOR TIBIALIS TENDON

POSTERIOR TIBIALIS TENDON

PERONEAL TENDON

SEMITENDINOSUS TENDON

FLEXOR DIGITORUM COMMUNIS TENDON

GRACILIS TENDON

FEMORAL HEAD

CONDYLE
BIOSCAFF® H
BIOSCAFF® H is a porous matrix for neurosurgery applications. Its innovative manufacturing process allows for collagen isolation from different human tissues, as well as a precisely controlled chemical process for optimal crosslinking degree. BIOSCAFF® H is highly adherent and is available in different sizes to meet different surgery needs.


Installations

The processing and CEyE areas have an ISO 7 Class 10,000 classification **, the input warehouses and tissue reception are unclassified controlled areas; however, it should be noted that all areas have sanitary finishes and controlled air in accordance with their classification.
*Biosecurity: Non-viable suspended particles > 0.5 mm/m33 up to 3,520 Viable particles up to 1 CFU/m33
**Biosecurity: Non-viable suspended particles > 0.5 mm/m33 up to 352,000 Viable particles up to 10 CFU/m33
- Cleaning and cutting the tissue
- Tissue lyophilization
- Tissue conditioning
- Bone demineralization
- Amniotic membrane processing
- Processing of meshed and laminar skin
- Cell Culture area
It has specialized equipment for tissue processing, such as:
Freeze dryers, ISO 5 class 100* biological safety cabinets and freezing equipment for
the temporary storage of tissue in process.
- Autoclave
- Drying oven
- Water purification system (Milli-Q Integral Millipore)
Storage of musculoskeletal tissue
- Ultra-Low Freezers
- Freezers
- Refrigerators
Finished products storage
- Ultra-Low Freezers
- Cryomed
- Cryoplus
Supplies storage
- 304L grade stainless steel furniture